Research

The main thrust of my early research has been into post natal disorders and I received the Gaskell research prize of the Royal College for this in 1982. I was interested in the psychobiological changes that occurred in conjunction with the maternity Blues and conducted studies on body weight changes, electrolytes tryptophan and hormones in the early post partum period. I wrote a lengthy and oft quoted review of these changes and I have spent many years studying issues around childbirth.

Another important contribution is a lithium augmentation trial of tricyclics that I conducted together with Dr. Morris Bernadt This was one of the largest RCTs on the subject in the world and is one of two British trials on the subject and it is widely quoted in the literature. and this treatment is a widely used treatment strategy for the treatment of resistant depression

Publications

COPPEN, A, STEIN, G S. and WOOD, K. Postnatal depression and Tryptophan metabolism Chapter 2 p25 34 in Mental illness in Pregnancy and the Puerperium. Oxford Oxford University Press

STEIN, G S, MILTON, E. and BEBBINGTON, P. (L976) Relationship between mood disturbances and free and total plasma Tryptophan in post partum women. British Medical Journal, 2, 457.

STEIN, G.S, MORTON, J and KEATING, P. (l978) Peri-partum cardiac failure. The Lancet, l2l4.

STEIN, G.S. (l979) An enquiry into the nature and aetiology of the maternity blues syndrome. (M.Phil.Thesis) London University.

STEIN, G S, HOLMES, J, BRADFORD J.W, and KENNEDY, L. (l980) HLA antigens and affective disorder. A family case report. Psychological Medicine, 677 -68l.

STEIN, G S, EBELING and DESAGA, U. (l980) Vasopressin in the first post partum week. Xl International Congress of Psychoneuroendrinology, Florence.

STEIN, G S (l980) The Pattern of Mental Change and Body Weight change in the first post partum week. Journal of Psychosomatic Research, l65 -l7l.

STEIN, G S. (l98l) Headaches in the First Post Partum Week and Their Relationship to Migraine. Headache, 20l - 205.

STEIN, G S, MARSH, A and MORTON, J. (l98l) Mental symptoms, weight changes and electrolyte excretion in the first post partum week. Journal of Psychosomatic Research.

STEIN, G S, PATNA, V J M, CHU, M and CASALE, J. (l98l) A large group in a district general hospital. British Journal of Medical psychology, 329 - 334.

STEIN, G S. (l982) Dangerous episodes occurring around the time of discharge of four chronic schizophrenics. British Journal of Psychiatry, 586 - 589.

STEIN, G S, HARTSHORN, S, JONES, J and STEINBERG, D. (l982) Lithium in a case of severe Anorexia Nervosa. British Journal of Psychiatry, 526 - 528.

STEIN, G S (l982) The Maternity Blues. Chapter 5 in Motherhood and Mental Illness, ed. Kumer and Brockington, Academic Press.

STEIN, G S. (l983) Second Opinion. A women with post-natal depression. Modern Medicine, 29 - 37.

STEIN, G S. (l984) Pre-eclampsia and post-partum migraine. The Lancet, 87l STEIN, G S, MORTON, J, MARSH, A, HARTSHORN, J, EBELING, J and DESAGA, U. (l984) Vasopressin and Mood During the Puerperium. Biological Psychiatry, l7ll -l7l7.

STEIN, G S. (l984) Emotional reactions to childbirth: Maternity Blues. Modern Medicine, 3l - 35.

STEIN, G S, MORTON, J, MARSH, A, COLLINS, W, BRANCH, C, DESAGA, U and EBELING, J. (l984) Headaches after Childbirth. Acta Neurol. Scand., 74 - 79.

PUCHES, A. and STEIN, G S. (l985) Puerperal psychosis: New thinking on women at risk. Modern Medicine, ll.

JOBLING, M. and STEIN, G S. (l986) Lorazepam in resistant mania. The Lancet, 5l0.

NODARAJAH, J. and STEIN, G S. Piroxicam induced Lithium toxicity. The Lancet, 502.

DEWSNAP, P. and STEIN, G S. (l988) Understanding Depression: The mechanism of antidepressant drug. action. Modern Medicine, 1 -4

STEIN, G S, ROBERTSON, M and NADARAJAH, J (l988) Toxic interactions between Lithium and non steroid anti-inflammatory drugs. Psychological medicine, 535 - 543

STEIN, G S and BERNADT, M. (1988) Double blind trial of Lithium Carbonate in tricyclic resistant depression. 2nd Worlds Lithium Congress.

AHMED, S and STEIN, G S. (l988) Negative Interaction between Lithium and ECT. British Journal of Psychiatry.

DEWSNAP, P and STEIN, G S. A case of malaria. British Journal of Psychiatry.

EL KOMY, A, STEIN G S and HARWIN, B G. (1988) Psychotic Depression associated with Benzodiazepines withdrawal. Egypt. J. Psychiat.

GHAZZIUDIN, M, GHAZIUDDIN, N and STEIN G S. (1990) Life events and the recurrence of depression. Can. J. Psych.

VAN DER AKKER, O and STEIN, G S. (1987) PMT Genetics of PMT. Acta Gemellogica.

STEIN, G (l992) Drug Treatment of the Personality Disorders, British Journal of Psychiatry, l6l, l67 - l84.

STEIN, G S (l993) Authors reply. Drug Treatment of Personality Disorders, British Journal of Psychiatry, l62, l23.

EDWARDS, D, PORTER, S and STEIN, G S. (l994) A pilot study of post natal depressionn using two reprospective rating scales in caeserian section. Caesarian section and Post Natal Depression in press Journal Psychosomatic research.

STEIN, G S,and BERNADT, M. Lithium augmentation - a controlled trial. British Journal of Psychiatry, May l993.

Personality Disorders Reviewed Eds. G Stein and P Tyrer. Gaskell Press, June l993

TYRER, P and STEIN, G (l993) Personality Disorders Reviewed, London. Gaskell Press.

STEIN, G (l993) Drug Treatment of the Personality Disorders, Chapter l2 in Personality Disorders Reviewed, p. 262 - 304.

STEIN, G (l994) Physical Treatment of the Personality Disorders, Current Opinion 7, 129 - 136

Stein, G and Bernadt, M. (1993) Lithium Augmentation Therapy in tricyclic resistant depression.

A controlled trial using Lithium in low and normal doses. British Journal of Psychiatry. 162, 634 – 640.

Stein, G. (1995) Drug Treatment f the Personality Disorders. Premenstrual tension, Impotence and Male sexual suppressants. Chapter 13 in College Seminars in Psychopharmacology. Ed. D. J. King, London, Gaskell press.

Edwards, D., Porter, S and Stein, G.( 1995) A pilot study of Postnatal Depression following Caesarean Section using two retro-spective self-rating instruments, Journal of Psychosomatic Research 38 (2) 111 – 117.

O.B.A. Van der Akker, F.P. Eves, G.S. Stein and R.M. Murray (1996) Genetic and Environmental features in Premenstrual Symptom and its relationship to depression and a general trail. British Jouirnal of Psychosomatic research, 39, 4, 477 – 487.

Hamid, W., Cooney, C., Stein, G. 1996, The Organiser and the MRCPsych Exam: The College’s instruction versus Murphy’s Law, Psychiatric Bulletin, 20, 681 – 682.

Stone, M, Casey, P., Stein, G. Treatment and outcome of the Personality Disorders, Chapter 19 in College Seminars in Adult General Psychiatry. (1998) P. 815 – 857. Eds. G Stein and G. Wilkinson, London, Gaskell press.

Pfeffer, J. and Stein, G Diagnosis, Classification and Measurement. (1998) Chapter 26 P.1229 – 1273 in College Seminars in Adult General Psychiatry (1998). Eds. G. Stein and G. Wilkinson, London, Gaskell press.

STEIN, G. Drug Treatment of Personality Disorders. Current opinion (l994 April l995

Jha, A.K., Fenwich, P. and Stein, G. Decreased Efficacy of Combined benzodiazepines and unilateral ECT in the treatment of depression. (1996) Acta Psychiatric Scandanavica, 94, 101 – 104.

Stein, G. (1997) Development of Affiliate status. Psychiatric Bulletin 21, 405 – 407. Usefulness of the Health of the nation scales. Editorial 1999. British Journal of Psychiatry.

Access to health records: Psychiatric patients and patients with diabetes compared (1998) Psychiatric Bulletin, 22, 95 - 98

Stein G and Wilkinson G (1998) College Seminars In Adult General Psychiatry 1392pp. London Gaskell.

SERIES EDITOR (Together with H FREEMAN, I PULLEN, and G WILKINSON).

College Seminars in Child and adolescent Psychiatry. Editors, Dora Black and David Cottrell (l993) London, Gaskell.

College Seminars in Psychology and the Social Sciences. TANTUM, D and BIRCHWOOD, M, London, Gaskell.

College Seminars in Practical Forensic Psychiatry, CHISWICK, D and COPE, R. (l995) London, Gaskell.

College Seminars in Alcohol and Drug Misuse, CHICK, J, and CANTWELL, R (l994) London, Gaskell.

Seminars in Basic Neurosciences, Editors Gothin Morgan and Stewart Butler, London, Gaskell (l993)

Seminars in Psychiatric Genetics by Peter McGaffin, M J, Owen, M C O'Donovan, Anita Thapar, II Gottesman, London, Gaskell (l994).

Seminars in Clinical Psychopharmacology. Editors, David King. London, Gaskell (l995)

Perinatal Psychiatric Disorders. George Stein Chapter 25 p635-638 in College Seminars in Adult general psychiatry (2007) Eds G. Stein and G. Wilkinson (2007) London Gaskell Press

Seminars in in adult General Psychiatry (2007) Eds G. Stein and G. Wilkinson London; Gaskell Press 810pp

(This is my most important publication and is a huge textbook of psychiatry)

REFERENCES OF THE BIBLICAL THEOLOGICAL WORK

3. Stein G. Morbid jealousy may have been recognised in the Old Testament. British Journal of Psychiatry. 2011;198:142.

4. Stein G. Early Child Psychiatry. British Journal of Psychiatry. 2010;197:105.

5. Stein G. Hannah: a case of infertility and depression. British Journal of Psychiatry. 2010;197(6):492.

6. Stein G. The case of King Saul: did he have recurrent unipolar depression or bipolar affective disorder? British Journal of Psychiatry. 2011;198:212.

7. Stein G. Alcoholism in Ancient Israel. British Journal of Psychiatry. 2008;193(2):113.

8. Stein G. Was the scoundrel (belial) of the Book of Proverbs a psychopath? British Journal of Psychiatry. 2009;194(1):33.

9. Stein G. The essa zarah, the strange women of the Book of Proverbs. British Journal of Psychiatry. 2009;195:293.

10. Stein G. Lost in translation: the biblical classification of personality disorder. British Journal of Psychiatry. 2008;193:337.

11. Stein G. Psalm 38: A man with major depression. British Journal of Psychiatry. 2010;196:309.

12. Stein G. Did the author of Psalm 30 have cyclothymia or bipolar disorder? British Journal of Psychiatry. 2009;195(6):550. 13. Stein G. Paranoia in the Psalms. British Journal of Psychiatry. 2010;197(4):284.

14. Stein G. Did Ezekiel have catatonia? British Journal of Psychiatry. 2008;193(3):253.

15. Stein G. Did Ezekiel have first-rank symptoms? British Journal of Psychiatry. 2009;194:551.

16. Stein G. The voices that Ezekiel hears. British Journal of Psychiatry. 2010;196(2):101.